ea0086p193 | Endocrine Cancer and Late Effects | SFEBES2022
Samson Aina Olawale
, Iranloye Bolanle
, Ckukwuduben Evangelshane
, Rotimi Adebayo
Endocrine therapy in hormone sensitive cancers is on the increase and substances that reduce estrogen level and upregulate estrogen receptor can reduce activities of ovarian cancer. Clomiphene citrate (CC) is a selective estrogen receptor modulator. This study is aimed at investigating how different doses of CC affect estrogen level and level of alpha and beta estrogen receptors in the ovary of adult female rats. Fifty female Sprague-Dawley (SD) rats were divided into 5 groups...